STX HTS EVOM™ Electrode

For high throughput screening (HTS) in cell culture filter plates

Features

• Designed for use with 24-well HTS plate (Corning Costar and Corning Falcon) and with 96-well plates (Millipore)
• Improved accuracy down to 5 Ω
• Sterilized with EtO, alcohol or bactericide
• Compatible with EVOM, EVOM™ Manual, Millicell^® ERS and ERS2
• STX4 Electrode adapter cable is required to use with EVOM, EVOM2, Millicell^® ERS and ERS2 

Options

Benefits

• Smaller tip size than the STX2 electrode constructed for durability fits neatly into the keyhole shaped filter well
• Electrode design reduces chance of contamination
• Premium Warranty Available

Applications

• STX HTS EVOM™ Electrode are designed for TEER measurement in HTS culture plates using the EVOM Manual

Semi-permeable HTS (high throughput screening) culture plates have become a standard tool for pharmaceutical and institutional research in epithelial transport. HTS culture plates have well cups which are bonded together into a single assembly and are not removable. This makes the plates ideal for automated applications, but imposes a significant inconvenience when TEER must be measured in the absence of an automated system. WPI’s STX HTS series of EVOM™ electrodes provide a cost-effective alternative to automation, allowing HTS well plates to be measured manually using a hand–held electrode.

The spatial orientation of an electrode during TEER measurement can have a significant effect on the resistance reading. When compared to the STX-2 “chopsticks” electrode, the STX HTS series of EVOM™ electrodes offer a technical advantage. The design of the STX HTS series of EVOM™ electrodes guarantees spatial repeatability. Each STX HTS EVOM™ Electrode is designed to self-align based on the form factor of the apical and basal access ports of the HTS plate. Each manufacturer of HTS culture systems has a unique form factor, and the correct STX HTS EVOM™ Electrode to use is manufacturer specific.

WPI developed STX HTS EVOM™ Electrode for 24 and 96 well plates specific to Corning, Corning Falcon and Millipore. Refer to the charts for compatibility information or contact your WPI sales representative for assistance. If an automated system is preferable for your application, investigate WPI’s automated TEER measurement system (EVOM™ Auto).

Compatibility charts

The STX HTS EVOM™ Electrode is compatible with the following Millpore plates.

STX HTS EVOM™ Electrode for Millipore	Part #	Description	Pore size	Membrane
EVM-EL-03-03-02	PSHT004R1	96-well plate	0.4um	PCF
	PSRP004R1	96-well plate	1.0um	PET
	PSHT004R5	96-well plate	0.4um	PCF
	PSRP004R5	96-well plate	1.0um	PET
	PSHT004S5	96-well plate	0.4um	PCF
STX HTS EVOM™ Electrode for Corning 96	PN	Description	Pore Size	Membrane
EVM-EL-03-03-05	3380	HTS Transwell-96 System	1.0μm	PET
	3392	HTS Transwell-96 System	1.0μm	PET
	7369	HTS Transwell-96 System	0.4μm	PET
	3381	HTS Transwell-96 System	0.4μm	PC
	3391	HTS Transwell-96 System	0.4μm	PC
	3385	HTS Transwell-96 Well Plate	3.0μm	PC
	3386	HTS Transwell-96 Well Plate	3.0μm	PC
	3387	HTS Transwell-96 Well Plate	5.0μm	PC
	3388	HTS Transwell-96 Well Plate	5.0μm	PC
	3374	HTS Transwell-96 Well Plate	8.0μm	PET
	3384	HTS Transwell-96 Well Plate	8.0μm	PET
STX HTS EVOM™ Electrode for Falcon	PN	Description	Pore Size	Membrane
EVM-EL-03-03-03	351181	Corning Falcon HTS Multiwell Insert System	1.0μm	PET
	351183	Corning Falcon HTS Multiwell Insert System	3.0μm	PET
	351185	Corning Falcon HTS Multiwell Insert System	8.0μm	PET
	354803	Corning BioCoat HTS Fibrillar Collagen Multiwell Insert System	1.0μm	PET
	354804	Corning BioCoat HTS Fibrillar Collagen Multiwell Insert System	1.0μm	PC
STX HTS EVOM™ Electrode for Corning 24	PN	Description	Pore Size	Membrane
EVM-EL-03-03-04	3378	HTS Transwell-24	0.4μm	PET
	3379	HTS Transwell-24	0.4μm	PET
	3396	HTS Transwell-24	0.4μm
	3397	HTS Transwell-24	0.4μm
	3398	HTS Transwell-24	3.0μm
	3399	HTS Transwell-24	3.0μm

Sample plates

Click to enlarge.	Click to enlarge.	Click to enlarge.	Click to enlarge.
This is a Corning #3378 24-well plate that may be used with the EVA-EL-03-02 or the EVM-EL-03-03-04. The Corning Falcon 24-well plate is virtually identical to this one, and it may be used with the EVM-EL-03-03-03.	This is a Corning Falcon 96-well plate that may be used with the EVA-EL-03-01.	This is a Millipore Multiscreen CaCo2 that may be used with the EVA-EL-03-01 or the EVM-EL-03-03-02.	This is a Corning 3391 HTS Traswell 96 plate that may be used with the EVA-EL-03-01 or the EVM-EL-03-03-05.