Biosensing
- - June 08, 2020
When using a TBR Free Radical Analyzer, accurate measurements of an analyte requires an accurate calibration. The calibration of nitric oxide, hydrogen peroxide and hydrogen sulfide sensors is similar. WPI oxygen and glucose sensors require different methods which will not be discussed here.
- - February 24, 2020
Nitric oxide (NO) is an essential signaling molecule and is known to play a significant role in a multitude of physiological systems including the central nervous system (CNS), the cardiovascular system, the gastrointestinal tract, the immune system, and the renal system. 1-5 However, being highly reactive, detection and quantification of NO is very difficult.6,7 It requires a sensor that is sensitive, selective to NO, and easy to calibrate.
WPI’s Free Radical Analyzer (4-channel TBR4100 and single-channel TBR1025) and the LabTrax Data Acquisition System with the options of using nano NO sensors, micro NO sensors, flexible micro sensors, and macro nitric oxide sensors enable amperometric (electrical based) detection of NO dissolved in liquids.
Features & Benefits of the Free Radical Analyzer and Nitric Oxide Detection System
- Rapid response time: < 5 sec enhances detection capability of the highly reactive, short-lived NO molecules
- High sensitivity: ≤2 pA/nM – enables detection...more
- - October 09, 2014
World Precision Instruments chemist Nikki Scafa demonstrates how to calibrate your ISO-OXY-2 or OXELP oxygen sensor with the TBR4100 free radical analyzer. For more information on biosensors, see www.wpiinc.com/biosensors.
- - April 29, 2013
A New Generation of Fiber Optic Oxygen Sensors Based on Luminescence Lifetime
Oxygen measurement is simpler than ever. Just stick a disposable, oxygen-sensitive "spot" to the inside of a flask, beaker, test tube or bottle, and fill the container
with the solution to be tested. Then, on the outside of the glass container, hold the fiber optic wand close to the spot to take a reading. As the spot reacts with oxygen, it gives off light, which is measured with the fiber optic wand. This ingenious system is highly accurate and affordable. Two different units (which use the same operating principles are available: OXY-MINI and OXY-MICRO. The OXY-MINI system is optimized for process control and biotechnology applications. The OXY-MICRO is designed for biological research applications including
implanting into tissues, cell cultures, profiling of biofilms and sediment related bioassays. The measurement principle of the sensor system is based on the detection of oxygen concentration as a function...more - - April 28, 2013
Download a PDF version of the Biosensor Specifications Sheet here.
WPI offers a range of biosensors for monitoring nitric oxide, hydrogen peroxide, oxygen and hydrogen sulfide. Specifications for these sensors are detailed below.
- The macrosensors are 2mm "wet" sensors. These sensors are installed in a metal "sleeve" that looks like a tiny soda straw.The sleeve has a gas permeable membrane at the tip, and it is filled with an electrolyte. When it is immersed in a solution, the gas in solution (for example, nitric oxide) diffuses through the membrane, and the sensor measures it.
- The microsensors are "dry" sensors. Most microsensors monitor nitric oxide, and there is also a hydrogen peroxide microsensor available.
Macrosensors (2mm)
WPI's 2mm macrosensors are uniquely designed with an internal reference electrode. These sensors are designed for use with the TBR1025, or TBR4100. The ISO-OXY-2 and the OXELP sensors have the same specifications. However, they have different connectors...more
- - April 23, 2013
In this video, WPI Chemist Nikki Scafa demonstrates how to make a 0.1M solution of CuCl2 for calibrating WPI NO microsensors.
- - April 23, 2013
In this video, WPI Chemist Nikki Scafa demonstrates how to make a PBS buffer solution for use with WPI microsensors.
- - April 23, 2013
- - April 23, 2013
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