EVOM

Meet the EVOM™ Auto from World Precision Instruments, the breakthrough that’s revolutionizing drug discovery. When it comes to drug discovery, reliable data on barrier function and cell integrity is essential. Transepithelial Electrical Resistance (TEER) measurements have long been the gold standard for assessing barrier function and cell integrity, critical data for your research, but traditional TEER workflows are often slow, error‑prone, and labor‑intensive.

In traditional hanging-insert workflows, media changes are a slow, manual bottleneck. Researchers must lift each insert—often with tweezers—to access the narrow gap between insert and well for pipetting or aspiration. This labor-intensive step not only adds time and variability but also risks disturbing delicate cellular layers. Now, WPI’s 24-Well Auto Exchange Cell Culture Plate fundamentally reshapes this workflow by combining smart well geometry, integrated fluidics, and robust insert seating to enable fully automated, multichannel TEER measurement on the EVOM™ Auto—and to simplify every step of media exchange and sampling, whether done by hand or robot. It enables seamless media exchange and multichannel TEER measurements without ever lifting an insert.

The EVOM™ Auto with GxP module allows you to synchronize the date and time of the EVOM™ Auto system to the computer. This date is used to time stamp data when acquiring data and when staging it for export.

EVOM™ GxP compliance Module is 21 CFR Part 11 compliant software that meets the FDA's requirements for electronic records and signatures. When running the EVOM™ Auto with the GxP.

EVOM™ Auto is a high throughput screening (HTS) platform offering fast, non-invasive sample scanning by comparing electrical resistance measurements (transepithelial/transendothelial electrical resistance: TEER). TEER measurement experiments are simple to set up and less time consuming than more complex molecular studies. The GxP module offers 21 CFR Part 11 compliant software that is required by the FDA. In this video, we will see how to delete an EVOM™ Auto GxP measurement sequence you no longer need.

One of our frequently asked questions (FAQs) concerns TEER measurements with an EndOhm. If the resistance readings from your ENDOHM don't stabilize, you may need to do some troubleshooting.

WPI’s EVOM™ line of transepithelial electrical resistance (TEER) measurement systems use silver-silver chloride electrodes for taking measurements. Our newest automated TEER measurement unit, the EVOM™ Auto, is available with an optional GxP module to ensure 21 CFR Part 11 compliance. GxP represents the quality guidelines in place to ensure standards are met. It is used for protocols like Good Laboratory Practice, Good Pharmaceutical Practice, Good Clinical Practice, Good Manufacturing Practice, and Good Research Practice.

Regular maintenance keeps your EVOM™ Auto GxP electrodes performing optimally. Periodically, you will need to re-chloride your electrodes. Just follow the steps shown in this video.

EVOM™ Auto with GxP powered by TotalLab automates your TEER measurements with the confidence that your data security complies with FDA’s 21 CFR Part 11 regulations.

You may calibrate the electrode array head using the internal reference resistor. Nothing involving the motor movement happens.

The EVOM™ Auto automated TEER measurement system with the GxP module powered by TotalLab ensures that your data security complies with FDA 21 CFR Part 11 requirements. If you have customized parameters like electrode placement for a plate profile, you may reset all the parameter to their factory default settings. We’ll show you how.

EVOM™ Auto with the GxP module lets you perform automated transepithelial electrical (TEER) resistance with confidence that your data security complies with the FDA 21 CFR Part 11 regulations. Here we will see how to run or stop a scheduled measurement sequence.

WPI’s EVOM™ Auto simplifies transepithelial electrical resistance (TEER) measurement by automating measurements in 24- and 96-well plates. A GxP module powered by TotalLab is available to meet the FDA’s 21 CFR Part 11 compliance regulations. Before making measurements, you need to stabilize your electrodes. See how here.

EVOM™ Auto automates TEER measurement, and it is now available with a GxP module to meet the FDA’s 21 CFR Part 11 compliance regulations. Here we will see how to create a new project file in the EVOM™ Auto GxP client software. Two options are available for the GxP software, and creating a project works the same way in both Option A and Option B versions. However, you may only create a project with files in the EVOM™ Auto GXP Option A software. Option B only lets you store EVOM™ Auto data files in the project folder.

When your transepithelial electrical resistance (TEER) measurement processes require 21 CFR Part 11 compliance to satisfy FDA requirements, WPI’s GxP module for use with the EVOM™ Auto is perfect. Powered by TotalLab, the software database ensured that your EVOM™ Auto TEER data is tracked and stored with appropriate electronic signatures and an extensive audit trail. EVOM™ Auto can be used to perform automated TEER measurement on both 24- and 96-well plates. In this video you can see how to prepare your data for downloading.

WPI’s EVOM™ line of transepithelial electrical resistance (TEER) measurement systems is the industry standard with thousands of citations in peer-reviewed journals spanning over 40 years. Our newest automated TEER measurement unit, the EVOM™ Auto, works with both 24- and 96-well plates, and now it is available with an optional GxP module to ensure 21 CFR Part 11 compliance to satisfy FDA requirements. In this video you can see how to run, pause, and stop an experiment.