Page 11 - Blog

Cell therapies have revolutionized the field of regenerative medicine, offering promising treatments for a variety of medical conditions. Maintaining the safety, efficacy, and consistency of cell-based therapies is paramount for their successful application in clinical settings. Quality control measures play a vital role in evaluating the quality of these therapies, from development to administration. This article explores the current approaches to quality control in cell therapies, including the utilization of functional measurement techniques such as transepithelial electrical resistance (TEER), to ensure the quality and safety of these promising treatments.

Transepithelial electrical resistance (TEER) has emerged as a powerful tool in ophthalmology research and has become a standard method for study of retinal pigment epithelial (RPE) cell biology and the development of these cells as a therapeutic for retinal diseases such as Age-Related Macular Degeneration (AMD). The application of TEER in assessing the barrier function and integrity of RPE cell layers has significantly advanced our understanding of retinal diseases and paved the way for innovative therapeutic interventions including some of the most promising cell therapies to date. This article explores the use of TEER in ophthalmology research, with a focus on studies utilizing RPE cells for both research and clinical applications.

EVOM™ Auto, with both 24 and 96 HTS multiwell plate capability, is a high throughput screening (HTS) platform offering fast, noninvasive sample scanning by comparing electrical resistance measurements (transepithelial/transendothelial electrical resistance: TEER). TEER measurement experiments are simple to set up and less time consuming than more complex molecular studies. TEER measurement can be used as the primary scanning method to identify any physiological changes that can then be further evaluated by other methods. EVOM™ Auto can capture TEER measurements in 24 and 96 HTS multiwell plates from Corning, Millipore, or MatTek. The sample preparation time in these HTS plates is efficient, allowing for fast, multi-channel pipetting options.

The EVOM™ Auto autosampler ships with a red electrode array lock in place to prevent the electrode array connection port from moving during transit. Here you can see how to easily remove it without damaging the lock or the autosampler.

Below are some popular pullers from WPI, including Sutter pullers. Here we compare them so you can choose a system that is best suited for your application.

The WPSS01 skin stapler is an affordable, reliable solution for veterinary wound closures. A skin stapler is designed for the efficient closure of surgical incisions or wounds by applying surgical staples to the skin, reducing surgery time and time under anesthesia. Each disposable skin staple cassette contains at least thirty-five (35) 316L stainless steel staples.

Each reusable skin stapler handle is provided sterile with one disposable staple cassette already loaded into the handle. Discard the disposable staple cassette after the procedure. The reusable handle may be cleaned and resterilized (autoclave, EO) for subsequent procedures and will effectively deploy at least twenty (20) disposable staple cassettes and withstand at least twenty (20) autoclave cycles.

Surgical forceps are available in several different grades, including disposable, standard stainless steel, German steel, Swiss made, and titanium. Your choice of instrument grade will depend on your requirements and your budget. Here are some considerations to help you make an informed decision.

Choosing a dependable lab equipment supplier is crucial for ensuring the quality, reliability, and timely delivery of the equipment you require.  When your research is on the line, you need a company you trust, a supplier with a proven track record and a service team to back you up. Here are a few important considerations when selecting a lab equipment supplier.

Reducing hand fatigue while using surgical scissors is important, not only for your comfort, but also to maintain the precision of your work. Here are some tips to help reduce strain and minimize hand fatigue.