Page 23 - Blog

The DMF1000 is a microprocessor-controlled microforge designed for fabrication of both small patch clamp glass pipettes and larger injection pipettes. The DMF1000 can be used for polishing patch clamp pipettes, microforging holding pipettes, microforging beveled injection pipettes, and for calibrating pipette tips for microinjection. Here we will show you how to configure the DMF1000 controller.

1. Power up the DMF1000 unit. Connect the cord to the power input jack.
2. Turn the power switch on. Then, plug the filament pins into the rear panel of the controller and plug the filaments into the sockets. 
3. After initialization, the setting that had been stored in memory location 0 displays. The Heat and Timer displays illuminate, indicating that the unit is powered up. The first time the unit is turned on, both readouts display 000. The TIME selection is set to Auto. The MODE selection is Heat. The Air On light is off, and the Heat On light is off.
4. For demonstration, I will hold the filament...more

Inox, Titanium, Dumoxel®, Dumastar®, Antimagnetic... Have you ever looked at the variety of metal alloys for surgical instruments and laboratory tools and wondered which is best for your needs? Here's a brief rundown.

Stainless Steel (Inox)

Why Stainless Steel is the Standard Alloy for Surgical Instruments

Our standard line of instruments is manufactured of highest quality materials. They are made of austenitic 316 steel commonly known as “surgical steel” or “marine grade steel.” Stainless steel, also known as Inox (from the French word "inoxydable"), is highly corrosion resistant and it is a common choice of material for biomedical implants or body piercing jewelry. It is in compliance with ASTM F138. This WPI line is an excellent alternative to German surgical...more

The manual microsyringe pump is a convenient tool for precise manual injection of fluid using glass pipettes or similar injection devices. The design allows visual feedback of flow at the pipette tip. They can also be used as a manual micro syringe pump for perfusion or withdrawal of liquids. The resolution of the injection volume can be continuously varied from 10 nanoliters to the microliter range, depending on the syringe used. Here we show you how to setup your system.

1. Loosen the set screw on the  Adjustable Micrometer Mount, but do not remove it.
2. Tighten the thumb screw on the Ajdustable Micrometer Mount.
3. Insert the digital micrometer or the manual micrometer through the hole on the Adjustable Micrometer Mount. Then, tighen the set screw.
4. Loosen the set screw on the Syringe Piston Mount Bracket.
5. Install the Bracket on the Spindle of the Micrometer. Tighten the set screw on the Bracket
6.  Loosen the Syringe Piston Mount Bracket thumb screw and the Syringe Mount Bracket thumb...more

Do you want to take the next step in your CRISPR-CAS9 projects, making the injection of biomolecules in your cell lines more efficient? You can now increase the viability of injected embryos with WPI’s MICRO-ePORE, which offers improved repeatability and functionality for pinpoint cell penetration for targeted microinjections in transgenesis.

Improve Embryo Survival with Pinpoint Cell Penetration

Principle of MICRO-ePORE™ Technology

• Classic Microinjection of biomolecules with capillaries causes permanent damage to the cell membrane, and the chance of lysis is high.
• Electroporation is a shot-gun, random approach that cause lots of membrane holes in cells, also increasing the chance of lysis.
• The MICRO-ePORE uses a very localized rearrangement of the charged double lipid membrane, allowing the biomolecules solution to get into the cells during injection. This leaves the rest of the membrane intact, reducing lysis and improving cell survival.

MICRO-ePORE in the Field

The MICRO-ePORE...more

Scissors are cutting instrument with two blades joined together at a pivot point so that the sharp edges glide against each other to shear material that is between the blades. Micro scissors are often called Vannas or spring scissors. Fine tip scissors (like these Vannas) are ideal for use in very restricted spaces. Here we examine some of our popular Vannas scissors.

Ambidextrous Use

Vannas scissors are perfect for right- or left-hand use, and are designed for ophthalmological procedures and neurosurgical application, which require a delicate incision of tissue.

Less Tissue Trauma

You can make quick, accurate cuts with minimal tissue damage, because these fine scissor blades are sharp. Vannas scissors work well under a dissection microscope.

Curved or Straight Tips

Curve-tipped scissors are a good choice when you want to avoid cutting underlying tissues. Curved blades provide a better visual of the working area. Straight blades may be used for any type of incision.

The blade tips...more

WPI offers alkaline cleaners for the pharmaceutical, biotech, medical device, healthcare, precision engineering, and other sectors.

This video shows how to setup the heavy boom microscope stand (502004), which can be used with a PZMIII or PZMIV microscope head. The PZMIII and PZMIV require the 502009 76mm focus mount. The setup of the 505606 heavy boom stand is identical. The 505606 uses the 505610 focus mount that is designed for use with the Enhanced Reality Macroscope. The focus mounts are sold separately.

Stand Components

These are the pieces of the boom stand.

(1) Heavy Base

(1) Vertical Post

(1) Guard Ring

(1) Horizontal Bar

(1) Cross Block

(1) Anchoring Screw with Locking Washer

(1) Hex Key

(1) Clutch Handle

(3) Adjustment Knobs

(1) Boom Locking Screw

(1) Post Cap

Set Up the Stand

1. Set the heavy base up on one edge. This may require two people, because the base is heavy. Have one person position the vertical post in the recessed circle in the center of the top side of the base. The post will be perpendicular to the base. Let a second person place the locking washer on the anchoring screw and insert it into...more

This video shows how to setup the articulating arm clamp stand for a microscope (502007), which can be used with a PZMIII microscope head. The PZMIII requires the 502009 76mm focus mount. The setup of the 505607 articulating arm stand is identical. The 505607 uses the 505610 focus mount that is designed for use with the Enhanced Reality Macroscope. The focus mounts are sold separately.

Stand Components

These are the pieces of the stand.

(1) Table clamp base

(1) Middle horizontal bar

(1) Adjustable forearm

(2) Clutch handles

(2) Adjustment screws

(2) Ring washers (white)

Set Up the Stand

1. Loosen the two screws on the table clamp by rotating them counter-clockwise. Position the clamp so that it wraps around the edge of the table with the screws located under the table. Tighten the screws by rotating them clockwise to securely mount the stand on the table.
2. Place a white ring washer on top of the table clamp and line it up with the hole. Then, insert the post of the middle horizontal...more

This video shows how to setup the post stand for a microscope (502007), which can be used with a PZMIII microscope head. The PZMIII or PZMIV require the 504947 76mm focus mount. The setup of the 505608 post stand is identical. The 505608 uses the 505609 focus mount that is designed for use with the Enhanced Reality Macroscope. The focus mounts are sold separately.

Stand Components

These are the pieces of the stand.

(1) Base

(1) Vertical Post

(1) Vertical Post Extension

(1) Guard Ring Support

(1) Reversible Plate

(1) Clutch Handle

(1) Post Cap

(1) Focus Mount

504947 Focus Mount included with the 503102 stand, or

505609 Focus Mount included with the 505608 stand

(1) Instruction Manual

Set Up the Stand

1. Set the base flat on a solid table or work surface. Screw the threaded end of the vertical post into the black support block on the base. Use a hex key to tighten the screw in the side of the black support block to secure the vertical.
2. Screw the post extension into the top of the vertical...more

Stainless steel and polymers are two of the most popular material options for sterilization trays used in the pharmaceutical and medical industries. In terms of toughness, long shelf life and resistance to contaminant absorption, surgical stainless steel outperforms plastic trays, especially for medical usage. Stainless steel trays also have a lower total cost over time.